地區(qū): | 上海 |
簡介: | 上海 |
提供商: | SABio |
服務(wù)名稱: | PCR芯片 |
藥物轉(zhuǎn)運蛋白PCR芯片可用于研究表達(dá)轉(zhuǎn)運蛋白的84個關(guān)鍵基因的表達(dá)。轉(zhuǎn)運蛋白在藥理學(xué)上發(fā)揮了關(guān)鍵作用,影響藥物進(jìn)出細(xì)胞進(jìn)入和排出。對吸收、分布、代謝和排泄重要的轉(zhuǎn)運蛋白包含于芯片。此外,有助于敏感性和抗腫瘤細(xì)胞的轉(zhuǎn)運蛋白也在此芯片上。通過實時定量PCR的方法,研究者即能夠利用該芯片簡單可靠地同時檢測與藥物轉(zhuǎn)運有關(guān)的基因表達(dá)。 ABC Transporters: ABCA1, ABCA2, ABCA3, ABCA4, ABCA5, ABCA9, ABCA12, ABCA13, ABCB1 (MDR1), ABCB4, ABCB5, ABCB6, ABCB11, ABCC1 (MRP1), ABCC2 (MRP1), ABCC3 (MRP3), ABCC4, ABCC5 (MRP5), ABCC10, ABCC11, ABCC12, ABCD1, ABCD3, ABCD4, ABCF1, ABCG2 (BCRP), ABCG8, TAP1 (ABCB2), TAP2 (ABCB3). SLC Transporters: SLC2A1, SLC2A2, SLC2A3, SLC3A1, SLC3A2, SLC10A1, SLC10A2, SLC15A1, SLC15A2, SLC16A1, SLC16A2, SLC16A3, SLC19A1, SLC19A2, SLC19A3, SLC22A1, SLC22A2, SLC22A3, SLC22A6, SLC22A7, SLC22A8, SLC22A9, SLC25A13, SLC28A1, SLC28A2, SLC28A3, SLC29A1, SLC29A2, SLC31A1, SLC38A2, SLC38A5, SLC5A1, SLC5A4, SLC7A5, SLC7A6, SLC7A7, SLC7A8, SLC7A9, SLC7A11, SLCO1A2, SLCO1B1, SLCO1B3, SLCO2A1, SLCO2B1, SLCO3A1, SLCO4A1. Other Transporters: Vacuolar H+-ATPase: ATP6V0C. Copper Pumps: ATP7A, ATP7B. Aquaporins: AQP1, AQP7, AQP9. Major Vault Protein: MVP (LRP). Voltage-dependent Anion Channels: VDAC1, VDAC2. |