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凋亡PCR芯片96孔板Apoptosis PCR Array 96HT

科技服務 > PCR芯片實驗服務 > 凋亡PCR芯片96孔板Apoptosis PCR Array 96HT

凋亡PCR芯片96孔板Apoptosis PCR Array 96HT

凋亡PCR芯片96孔板Apoptosis PCR Array 96HT
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地區:上海
簡介:上海
提供商:SABio
服務名稱:PCR芯片
凋亡PCR芯片可用于研究參與細胞程序性死亡的84個關鍵基因的表達。細胞凋亡在正常生物過程中發揮重要作用,如分化、發育和體內平衡。應激反應,如熱休克、缺血、非折疊蛋白和病毒感染,會引起細胞嚴重受損甚至細胞凋亡。細胞凋亡經常導致不可控的細胞生長,如腫瘤形成和癌癥;同時腫瘤壞死因子(TNF)受體也會通過激活FADD和其他死亡受體蛋白引起凋亡。這一芯片包含了TNF配體及受體、bcl-2、半胱天冬酶、IAP、TRAF、CARD、死亡域、死亡效應域、CIDE家族,以及參與p53和DNA損傷通路的基因。研究這些基因的表達有助于確定在生物模型和細胞模型中的細胞機制。通過實時定量PCR的方法,研究者即能夠利用該芯片簡單可靠地同時檢測細胞凋亡相關基因的表達。
 
Apoptosis PCR ArrayHumanGene ExpressionPAHS-012Z
Apoptosis PCR ArrayHumanGene Expression 384HTPAHS-3012Z
Apoptosis PCR ArrayMouseGene ExpressionPAMM-012Z
Apoptosis PCR ArrayMouseGene Expression 384HTPAMM-3012Z
Apoptosis PCR ArrayRatGene ExpressionPARN-012Z
Apoptosis PCR ArrayRatGene Expression 384HTPARN-3012Z
Apoptosis PCR ArrayRhesus MacaqueGene ExpressionPAQQ-012Z
Apoptosis PCR ArrayChickenGene ExpressionPAGG-012Z
Apoptosis PCR ArrayPigGene ExpressionPASS-012Z
 
Induction of Apoptosis: Death Domain Receptors: CRADD, FADD, TNF, TNFRSF10B (DR5). DNA Damage: ABL1, CIDEA, CIDEB, TP53, TP73. Extracellular Signals: CFLAR (CASPER), DAPK1, TNFRSF25 (DR3). Other: BAD, BAK1, BAX, BCL10, BCL2L11, BID, BIK, BNIP3, BNIP3L, CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP3, CASP4, CASP6, CASP8, CD27 (TNFRSF7), CD70 (TNFSF7), CYCS, DFFA, DIABLO (SMAC), FAS (TNFRSF6), FASLG (TNFSF6), GADD45A, HRK, LTA (TNFB), NOD1 (CARD4), PYCARD (TMS1/ASC), TNFRSF10A, TNFRSF9, TNFSF10 (TRAIL), TNFSF8, TP53BP2, TRADD, TRAF3. Anti-Apoptosis: AKT1, BAG1, BAG3, BAX, BCL2, BCL2A1 (Bfl-1/A1), BCL2L1 (BCL-X), BCL2L10, BCL2L2, BFAR, BIRC3 (c-IAP1), BIRC5, BIRC6, BNIP2, BNIP3, BNIP3L, BRAF, CD27 (TNFRSF7), CD40LG (TNFSF5), CFLAR (CASPER), DAPK1, FAS (TNFRSF6), HRK, IGF1R, IL10, MCL1, NAIP (BIRC1), NFKB1, NOL3, RIPK2, TNF, XIAP (BIRC4). Regulation of Apoptosis: Negative Regulation: BAG1, BAG3, BCL10, BCL2, BCL2A1 (Bfl-1/A1), BCL2L1(BCL-X), BCL2L10, BCL2L2, BFAR, BIRC2 (c-IAP2), BIRC3 (c-IAP1), BIRC6, BNIP2, BNIP3, BNIP3L, BRAF, CASP3, CD27 (TNFRSF7), CD40LG (TNFSF5), CFLAR (CASPER), CIDEA, DAPK1, DFFA, FAS (TNFRSF6), IGF1R, MCL1, NAIP (BIRC1), NOL3, TP53, TP73, XIAP (BIRC4). Positive Regulation: ABL1, AKT1, BAD, BAK1, BAX, BCL2L11, BID, BIK, BNIP3, BNIP3L, CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP4, CASP6, CASP8, CD40 (TNFRSF5), CD70 (TNFSF7), CIDEB, CRADD, FADD, FASLG (TNFSF6), HRK, LTA (TNFB), LTBR, NOD1 (CARD4), PYCARD (TMS1/ASC), RIPK2, TNF, TNFRSF10A, TNFRSF10B (DR5), TNFRSF25 (DR3), TNFRSF9, TNFSF10 (TRAIL), TNFSF8, TP53, TP53BP2, TRADD, TRAF2, TRAF3. DEATH Domain Proteins: CRADD, DAPK1, FADD, TNFRSF10A, TNFRSF10B (DR5), TNFRSF11B, TNFRSF1A, TNFRSF1B, TNFRSF21, TNFRSF25 (DR3), TRADD. Caspases and Regulators: Caspases: CASP1 (ICE), CASP10 (MCH4), CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CFLAR (CASPER), CRADD, PYCARD (TMS1/ASC). Caspase Activators: AIFM1 (PDCD8), APAF1, BAX, BCL2L10, CASP1 (ICE), CASP9, NOD1 (CARD4), PYCARD (TMS1/ASC), TNFRSF10A, TNFRSF10B (DR5), TP53. Caspase inhibitors: CD27 (TNFRSF7), XIAP (BIRC4).


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