地區(qū): | 上海 |
簡介: | 上海 |
提供商: | SABio |
服務名稱: | PCR芯片 |
藥物轉運蛋白PCR芯片可用于研究表達轉運蛋白的84個關鍵基因的表達。轉運蛋白在藥理學上發(fā)揮了關鍵作用,影響藥物進出細胞進入和排出。對吸收、分布、代謝和排泄重要的轉運蛋白包含于芯片。此外,有助于敏感性和抗腫瘤細胞的轉運蛋白也在此芯片上。通過實時定量PCR的方法,研究者即能夠利用該芯片簡單可靠地同時檢測與藥物轉運有關的基因表達。 ABC Transporters: ABCA1, ABCA2, ABCA3, ABCA4, ABCA5, ABCA9, ABCA12, ABCA13, ABCB1 (MDR1), ABCB4, ABCB5, ABCB6, ABCB11, ABCC1 (MRP1), ABCC2 (MRP1), ABCC3 (MRP3), ABCC4, ABCC5 (MRP5), ABCC10, ABCC11, ABCC12, ABCD1, ABCD3, ABCD4, ABCF1, ABCG2 (BCRP), ABCG8, TAP1 (ABCB2), TAP2 (ABCB3). SLC Transporters: SLC2A1, SLC2A2, SLC2A3, SLC3A1, SLC3A2, SLC10A1, SLC10A2, SLC15A1, SLC15A2, SLC16A1, SLC16A2, SLC16A3, SLC19A1, SLC19A2, SLC19A3, SLC22A1, SLC22A2, SLC22A3, SLC22A6, SLC22A7, SLC22A8, SLC22A9, SLC25A13, SLC28A1, SLC28A2, SLC28A3, SLC29A1, SLC29A2, SLC31A1, SLC38A2, SLC38A5, SLC5A1, SLC5A4, SLC7A5, SLC7A6, SLC7A7, SLC7A8, SLC7A9, SLC7A11, SLCO1A2, SLCO1B1, SLCO1B3, SLCO2A1, SLCO2B1, SLCO3A1, SLCO4A1. Other Transporters: Vacuolar H+-ATPase: ATP6V0C. Copper Pumps: ATP7A, ATP7B. Aquaporins: AQP1, AQP7, AQP9. Major Vault Protein: MVP (LRP). Voltage-dependent Anion Channels: VDAC1, VDAC2. |