凋亡PCR芯片 384孔板 Apoptosis PCR Array 384HT
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| 地區： | 上海 |
| 簡介： | 上海 |
| 提供商： | SABio |
| 服務名稱： | PCR芯片 |
凋亡PCR芯片（384HT）可以用于檢測370個凋亡或細胞程序性死亡相關的關鍵基因。這款芯片涵蓋的基因包括：TNF配體及相應受體，bcl-2蛋白家族，BIRC結構域蛋白，CARD結構域蛋白，死亡效應結構域蛋白，TRAF結構域蛋白和半胱天冬酶。這370個基因可以按功能分類，分別在凋亡，DNA損失，氧化應激，或胞內和胞外信號等過程中發揮作用。通過實時定量PCR方法，研究者可以方便并且可信地對凋亡相關基因的表達進行集中分析。 Caspases & Regulators: Caspases: CASP1, CASP10, CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CFLAR (CASPER), CRADD, CARD18, CARD17, MALT1, PYCARD, RFWD2 (COP1). Caspase Activators: AIFM3, APAF1, BAX, BBC3, BCL2L10, BCL2L13, CASP1, CASP8AP2, CASP9, COL4A3, CYCS, DIABLO (SMAC), EIF2AK3, F2, F2R, FOXL2, HIP1, HSPE1, IFNB1, IFT57, LCK, MAP3K5, MOAP1, MTCH1, MYC, NLRC4, NLRP1, NLRP12, NLRP2, NLRP3, NOD1, PMAIP1, PYCARD, STAT1, TNFRSF10A, TNFRSF10B, TNFSF15, TP53, TPD52L1, VCP. Caspase Inhibitors: BIRC5, CD27 (TNFRSF7), DHCR24, HBXIP, IFI6, SFN, TNFAIP8, TNFSF14, TRIAP1, XIAP. Anti-Apoptosis: Positive Regulation: BCL2L1 (BCL-X), BRE, CD28, ERC1, MAPK8IP2, OPA1, PRKAA1, RASA1. Negative Regulation: PIK3R2, RTN4, TNFAIP8. Other genes: AATF, AKT1, ALOX12, ANXA1, ANXA4, API5, ATF5, AVEN, AZU1, BAG1, BAG3, BAG4, BCL2, BCL2A1, BCL2L1, BCL2L10, BCL2L2, BDNF, BECN1, BFAR, BIRC2, BIRC3, XIAP, BIRC5, BIRC6, BIRC7, BIRC8, BNIP1, BNIP2, BNIP3, BRAF, CASP2, CBX4, CCL2, CD27, CD40LG, CEBPB, CFDP1, CFL1, CFLAR, CRYAA, CRYAB, DAD1, DDAH2, DHCR24, EEF1A2, FAIM, FAIM2, FAS, FOXO1, GDNF, GFRAL, GLO1, GSTP1, HBXIP, HTT, HDAC1, HDAC3, HIPK3, HMGB1, HSP90B1, HSPA1B, HSPA9, HSPB1, HTATIP2, IER3, IFI6, IGF1R, IL10, IL1A, IL2, IL31RA, MALT1, MCL1, MKL1, MPO, MTL5, MYBL2, MYO18A, NAIP, NFKB1, NME5, NOL3, NOTCH2, NPM1, NRG2, NTF3, PAK7, PAX7, PEA15, PIK3CA, PIM2, POGK, POLB, PRDX2, PRKCZ, PRLR, PROK2, PSEN1, RELA, RNF7, SEMA4D, SERPINB2 (PAI-2), SERPINB9, SFRP1, SH3GLB1, SNCA, SOCS2, SOCS3, SON, SPHK1, SPP1, STAMBP, TAX1BP1, TBX3, TGFB1, TIAF1, TNF, TNFAIP3, TNFAIP8, TNFRSF10D, TNFRSF18, TNFRSF6B, TNFSF18, TPT1, TRIAP1, TSC22D3, TMX1, VEGFA, VHL, YWHAZ, ZC3HC1. Induction of Apoptosis: Death domain receptors: BID, CRADD, DAXX, DEDD2, FADD, IL18, TNF, TNFRSF10B. DNA damage: ABL1, AIFM1, BCL3, BRCA1, CHEK2 (RAD53), CIDEA, CIDEB, DYRK2, IFI16, MBD4, MSH6, PCBP4, PML, SFN, TP53, TP73. Oxidative stress: GPX1, PRODH, RNF7, TP53I3 Extracellular signals: ADORA1, BTK, CASP8AP2, CD28, CD38, CD5, CFLAR (CASPER), DAP, DAP3, DAPK1, DPF2, FASTK, MAP3K5, NDUFA13, PDCD6, PRKCA, RIPK3, SPN, TIMP3, TNFRSF25. Intracellular signals: CDKN1A, CUL1, CUL2, CUL3, CUL4A, CUL5, HIPK2, MYC, SART1. Other genes: ACVR1B, AIFM2, AIFM3, ALOX15B, APOE, BAD, BAK1, BAX, BBC3, BCL10, BCL2L11, BCL2L13, BCLAF1, BIK, BNIP1, BNIP3, BNIP3L, BOK, CASP10, CASP3, CASP4, CASP6, CD2, CD27, CD70, CEBPB, CIDEC, COL4A3, DAPK2, DAPK3, DCC, DDX20, DEDD, DIABLO (SMAC), EI24, ERCC2, ERCC3 (XPB), ERN1, ERN2, FAS, FASLG, FEM1B, FOXL2, FOXO3, HRK, HTATIP2, IFNA2, IFNB1, IFNG, IKBKG, IKBIP, IL19, INHA, INHBA, JMY, LALBA, LCK, LTA, MAL, MAP3K10, MAPK1, MX1, NDUFS3, NGFR, NLRP1, NLRP3, NME3, NOTCH2, NOX5, NUDT2, NUPR1, PDCD5, PLAGL1, PLAGL2, PLEKHF1, PLG, PMAIP1, PPP1R13B, PPP2CA, PPP2R1A, PPP2R1B, PRKCE, PRKRA, PRUNE2, PTEN, PTH, PYCARD, RPS3A, RUNX3, S100B, SAP30BP, SERINC3, SIPA1, SMNDC1, SST, SSTR3, STK17A, STK17B, TBX5, TIA1, TIAL1, TLR2, TNFRSF10A, TNFRSF19, TNFRSF9, TNFSF10, TNFSF14, TNFSF8, TP53BP2, TP63, TPD52L1, TRADD, TRAF3, TRAIP, UNC13B, UTP11L, ZNF443. TNF Domain: EDA, FASLG (TNFSF6), LTA, LTB, TNF, TNFSF10, TNFSF14, TNFSF15, TNFSF8. TNFR Domain: CD27 (TNFRSF7), CD40 (TNFRSF5), FAS (TNFRSF6), LTBR, NGFR, TNFRSF10A, TNFRSF10B, TNFRSF10D, TNFRSF18, TNFRSF19, TNFRSF1A, TNFRSF1B, TNFRSF21, TNFRSF25, TNFRSF6B, TNFRSF8, TNFRSF9. BCL2 and BAG Domain: BAG1, BAG3, BAG4, BAX, BCL2, BCL2A1, BCL2L1, BCL2L10, BCL2L13, BCL2L2, MCL1. BIR Domain: BIRC2 (c-IAP2), BIRC3 (c-IAP3), BIRC5, BIRC6, BIRC7, BIRC8, NAIP (BIRC1), XIAP. CARD Domain: APAF1, BCL10, BIRC2 (c-IAP2), BIRC3 (c-IAP1), CARD10, CARD11, CARD14, CARD6, CARD9, CASP1, CASP2, CASP4, CASP5, CASP9, CRADD, CARD18, CARD17, NLRP1,NOD1, NOD2, NOL3, PYCARD, RFWD2 (COP1), RIPK2. DEATH Domain: CRADD, DAPK1, EDAR, FADD, PIDD, MALT1, NFKB1, NFKB2, NGFR, RIPK1, TNFRSF10A, TNFRSF10B, TNFRSF1A, TNFRSF21, TNFRSF25, TRADD. TRAF Domain: TRAF2, TRAF3, TRAF5, TRAF7. Other Regulators of Apoptosis: BCL6, CEBPG, DBP, DDIT3 (GADD153/CHOP), GRM4, LGALS1, MADD, MAPK8, NKX3-2, POU4F1, PROP1, RARG, STAT5A, STAT5B, TBK1, TDGF1, TRAF6, ZAK. |
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